病理学研究部
独立研究員

仲本　博

研究テーマ
1) 糖尿病の合併症とC-peptideの関わり
2) 腎微小循環制御のメカニズム

学位・資格

1982年3月

大阪大学基礎工学部生物工学科　卒業

1989年3月

和歌山県立医大医学部医学科　卒業

1997年3月

川崎医大　医学博士

医師免許

日本内科学会認定内科医

日本内科学会総合内科専門医

第２種ME技術者（日本生体医工学会）

実用英語技能検定１級　（日本英語検定協会）

通訳案内士　(通訳ガイド、日本政府観光局)

所属学会

バイオレオロジー学会

日本循環器学会

日本腎臓学会

日本生体医工学会

日本内科学会

日本救急医学会

日本微小循環学会

米国心臓協会 (AHA)

主要論文

Hiroshi Nakamoto. Effects of C-peptide on the single-nephron glomerular filtration rate in early diabetic rats. Journal of Biorheology 34(1):2-8 2020

Hiroshi Nakamoto. Visualisation studies and glomerular filtration in early diabetic rats. J Biomech. 50:138-143 2017 (IF=2.431)

Nakamoto H. Transitions in the in-vivo visualisation of renal physiology J Biorheology 31(2):40-43 2017 (IF=0.27)

Nakamoto H, Nakayama K, Emoto N, Kajiya F. The Short-Term Effects of C-Peptide on the Early Diabetes-Related Ultrastructural Changes to the Podocyte Slit Diaphragm of Glomeruli in Rats Microcirculation 22 122-32 2015 (IF=2.532)

Nakamoto H, Kajiya F. In Vivo Quantitative Visualization Analysis of the Effect of C-Peptide on Glomerular Hyperfiltration in Diabetic Rats by Using Multiphoton Microscopy Microcirculation 20 425-433 2013 (IF=2.532)

Nakamoto H., Ogasawara Y., Kajiya F. In-vivo Visualisation of glomerular filtration by two-photon microscopy in a rat. In: Dössel O., Schlegel W.C. (eds) World Congress on Medical Physics and Biomedical Engineering, 2009, Munich, Germany. IFMBE Proceedings, vol 25/4. 1109–1110, 2009. (IF=0.21)

Nakamoto H, Ogasawara Y, Kajiya F. Visualisation of the effects of dilazep on rat afferent and efferent arterioles in vivo Hypertens Res. 31(2):315-24 2008 (IF=3.581)

Kimura K, Niijima A, Yoshida R, Kitamura T, Kamikawa A, Furuya DT, Kitamura N, Konno A, Nakamoto H, Sakane N, Yoshida T, Saito M Proinsulin C-peptide activates vagus efferent output in rats Peptides 26(12) 2547-53 2006 (IF=2.778)

Kiyooka T, Hiramatsu O, Shigeto F, Nakamoto H, Tachibana H, Yada T, Ogasawara Y, Kajiya M, Morimoto T, Morizane Y, Mohri S, Shimizu J, Ohe T, Kajiya F. Direct observation of epicardial coronary capillary hemodynamics during reactive hyperemia and during adenosine administration by intravital video microscopy Am J Physiol Heart Circ Physiol 288(3) H1437-43 2005 (IF=3.348)

Mochizuki S, Chiba Y, Hiramatsu O, Tachibana H, Nakamoto H, Toyota E, Ogasawara Y, Kajiya F. Direct measurement of nipradilol-derived nitric oxide in the vascular wall of canine femoral arteries.Heart Vessels 20(4):175-8. 2005 (IF=3.434)

Nakamoto H, Sakane N, Kimura K, Yoshida T, Mochizuki S, Ogasawara Y, Kajiya F. Synergistic effects of C-peptide and insulin on coronary flow in early diabetic rats Metabolism 53 335-39 2004 (IF=5.777)

Mochizuki S, Sipkema P, Goto M, Hiramatsu O, Nakamoto H, Toyota E, Kajita T, Shigeto F, Yada T, Ogasawara Y, Kajiya F. Exogenous NO suppresses flow-induced endothelium-derived NO production because of depletion of tetrahydrobiopterin Am J Physiol Heart Circ Physiol 288 H553-558 2004 (IF=3.348)

Yada T, Goto M, Hiramatsu O, Tachibana H, Toyota E, Nakamoto H, Ogasawara Y, Matsuda H, Arakawa K, Hayashi K, Suzuki H, Kajiya F. In vivo visualization of subendocardial arteriolar response in renovascular hypertensive hearts Am J Physiol Heart Circ Physiol 284 H1785-1792 2003 (IF=3.348)

Kiyooka T, Hiramatsu O, Shigeto F, Nakamoto H, Tachibana H, Yada T, Ogasawara Y, Kajiya M, Morimoto T, Morizane Y, Mohri S, Shimizu J, Ohe T, Kajiya F. Direct in vivo visualization of rat coronary capillary hemodynamics by intravital pencil lens-probe CCD videomicroscopy Microcirculation Annual 18 121-122 2002 (IF=unkonwn)

Ohta S, Nakamoto H, Shinagawa Y, Tanikawa T. A health monitoring system for elderly people living alone J Telemed Telecare. 8(3):151-6.2002 (IF=2.008)

Yamamoto T, Hayashi K, Matsuda H, Kubota E, Tanaka H, Ogasawara Y, Nakamoto H, Suzuki H, Saruta T, Kajiya F. In vivo visualization of angiotensin II-and tubuloglomerular feedback-mediated renal vasoconstriction Kidney Int. 60(1):364-9. 2001 (IF=8.395)

Merkus D, Vergroesen I, Hiramatsu O, Tachibana H, Nakamoto H, Toyota E, Goto M, Ogasawara Y, Spaan JA, Kajiya F. Stenosis differentially affects subendocardial and subepicardial arterioles in vivo Am J Physiol Heart Circ Physiol.280(4):H1674-82.2001 (IF=3.348)

Mochizuki S, Himi N, Miyasaka T, Nakamoto H, Takemoto M, Hirano K, Tsujioka K, Ogasawara Y, Kajiya F. Evaluation of basic performance and applicability of a newly developed in vivo nitric oxide sensor Physiol Meas. 23(2):261-8. Erratum in: Physiol Meas. 2002 Aug;23(3):597.2002 (IF=2.058)

Ogasawara Y, Takehara K, Yamamoto T, Hashimoto R, Nakamoto H, Kajiya F. Quantitative blood velocity mapping in glomerular capillaries by in vivo observation with an intravital videomicroscope. Methods Inf Med.39(2):175-8. 2000 (IF=1.531)

Toyota E, Goto M, Nakamoto H, Ebata J, Tachibana H, Hiramatsu O, Ogasawara Y, Kajiya F. Endothelium-derived nitric oxide enhances the effect of intraaortic balloon pumping on diastolic coronary flow Ann Thorac Surg.67(5):1254-61.1999 (IF=3.700)

Ohta S, Ogasawara Y, Matsumoto T, Hiramatsu O, Nakamoto H, Okamoto T　Analysis of coronary hemodynamics by coronary circulation model with three layered myocardium Comput Cardiol.673-676 1995 (IF=0.45)

Nishida K, Takano H, Ohtsuki T, Yoneda M, Nakamoto H, Terasawa Y, Yamane E, Nishioka B, Namura K, Yoshikawa T, Kondo M. Flow cytometric analysis of nuclear DNA content in the endoscopic biopsy tissues of gastric cancer Am J Clin Oncol.18(4) 325-30 1995 (IF=3.259)